CAS:1313874-96-2|Afatinib-d6

Catalogue Number:A355303
Chemical Name:Afatinib-d6
Synonyms:(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide-d6; BIBW 2992-d6;
CAS Number:1313874-96-2
Alternate CAS #
unlabelled: 850140-72-6
Molecular Formula:C₂₄H₁₉D₆ClFN₅O₃
Appearance:White to Pale Yellow Solid
Molecular Weight:491.98
Storage:-20°C
Solubility:DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Afatinib-d6 is the d6 labelled analogue of Afatinib (A355300) which is an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
References:Schroeder, J., et al.: PCT Int. Appl. WO 2007085638 A1 20070802. Aug 2, 2007;
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