Deoxynojirimycin-d2, 15N Hydrochloride

Chemical Name:Deoxynojirimycin-d2, 15N Hydrochloride
Synonyms:(2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol-d2, 15N Hydrochloride; 1-Deoxynojirimycin-d2, 15N Hydrochloride; AT 2220-d2, 15N; Duvoglustat-d2, 15N Hydrochloride; Moranoline-d2, 15N Hydrochloride; DNJ-d2, 15N Hydrochloride
Alternate CAS #:unlabelled: 73285-50-4
Molecular Formula:C₆H₁₂D₂Cl¹⁵NO₄
Molecular Weight:202.64
Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Deoxynojirimycin-d2, 15N Hydrochloride is the labeled analogue of Deoxynojirimycin Hydrochloride (D245005), which inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase.
References:Eur. J. Biochem., 142, 85-90 (1984); Crit. Rev. Biochem., 16, 21-48 (1984); Biochem. Biochem. Acta. , 825, 95 (1985); Suhm, K., et al.: J. Biol. Chem., 267, 21671 (1992)
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