Desmethyl Cariprazine Hydrochloride

Chemical Name:Desmethyl Cariprazine Hydrochloride
Synonyms:N-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N’-methyl Urea Hydrochloride
CAS Number:1231947-91-3
Alternate CAS #:Free Base: 839712-15-1
Molecular Formula:C₂₀H₃₀Cl₂N₄O •xHCl
Molecular Weight:413.38+x(36.46)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Desmethyl Cariprazine Hydrochloride is a derivative of Cariprazine (C183490) which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.
References:Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010); Seneca, N. et al.: Psychopharmacology, 218, 579 (2011); Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010)
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