Catalogue Number:A521150
Chemical Name:Alectinib M4 metabolite
Synonyms:9-Ethyl-6,11-dihydro-8-[4-[(2-hydroxyethyl)amino]-1-piperidinyl]-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
CAS Number:1256585-04-2
Molecular Formula:C₂₈H₃₂N₄O₂
Appearance:Off-White to Pale Brown Solid
Melting Point:>200°C
Molecular Weight:456.58
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Alectinib M4 metabolite is the major active metabolite of Alectinib. Alectinib is an anaplastic lymphoma kinase (ALK) inhibitor and is used to treat non-small-cell lung cancer by blocking the activity of anaplastic lymphoma kinase (ALK).
References:Heinig, K., et al.: Bioanalysis, 8, 1465-79 (2016); Morcos, P.N., et al.: Xenobiotica, 47, 217-29 (2017);
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Posted inMaterials
CAS:1256585-04-2|Alectinib M4 metabolite
