CAS:1617-53-4|Amentoflavone

Catalogue Number:A576420
Chemical Name:Amentoflavone
Synonyms:8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4′,4”’,5,5”,7,7”-hexahydroxy- (7CI,8CI); Ginkgetin, didemethyl-3”’,8-biflavone; Amenthoflavone; I3′,II8-Biapigenin; NSC 295677; Tridemethylsciadopitysin;
CAS Number:1617-53-4
Molecular Formula:C₃₀H₁₈O₁₀
Appearance:Pale Yellow to Yellow Solid
Melting Point:>300°C
Molecular Weight:538.46
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated), Pyridine (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Amentoflavone, is isolated from an Et acetate ext. of the whole plant of Selaginella tamariscina. It has been shown to have antitumor activity, such as mitochondria-mediated apoptotic cell death. Amentoflavone can interact with many medications by being a potent inhibitor of CYP3A4 and CYP2C9, which are enzymes responsible for the metabolism of some drugs in the body.
References:Jen-Sheng, P. et al.: In Vivo, 26, 963 (2012); Kimura,Y. et al.: Food Chem. toxicol., 48, 429 (2010);
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