CAS:60166-98-5|5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide

Catalogue Number:A601550
Chemical Name:5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide
Synonyms:USP Iopamidol Related Compound A; Iopamidol EP Impurity A
Impurity:Iopamidol EP Impurity A
CAS Number:60166-98-5
Molecular Formula:C₁₄H₁₈I₃N₃O₆
Appearance:White to Off-White Solid
Melting Point:>260°C (dec.)
Molecular Weight:705.02
Storage:4°C
Solubility:DMSO (Sparingly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide (Iopamidol EP Impurity A) is an impurity in the synthesis of Iopamidol (I735600), a nonionic radiocontrast medium. Diagnostic aid (radiopaque medium).
References:Drayer, B., et al.: Am. J. Neuroradiol., 3, 59 (1982), Molyneux, A.J., et al.: Br. J. Radiol., 55, 117 (1982), Sovak, M., et al.: Radiology, 142, 115 (1982), Felder, E., et al.: Anal. Profiles Drug Subs., 17, 115 (1988),
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