CAS:27511-79-1|3-Amino-4-carbamoylpyrazole Hemisulfate

Catalogue Number:A603076
Chemical Name:3-Amino-4-carbamoylpyrazole Hemisulfate
Synonyms:3-Amino-1H-pyrazole-4-carboxamide Hemisulfate; 3-Amino-Pyrazole-4-carboxamide Hemisulfate; USP Allopurinol Related Compound A; Allopurinol EP Impurity AAllopurinol EP Impurity A ; Allopurinol USP Related Compound A
Impurity:Allopurinol EP Impurity A / Allopurinol USP Related Compound A
CAS Number:27511-79-1
Alternate CAS #
freebase: 5334-31-6
Molecular Formula:C₄H₆N₄O•0.5H₂SO₄
Appearance:White to Pale Brown Solid
Melting Point:223-226°C
Molecular Weight:126.12 + 0.5(98.08)
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Very Slightly), Water (Slightly, Heated, Sonicated)
Stability
Hygroscopic
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Amino-4-carbamoylpyrazole Hemisulfate (Allopurinol EP Impurity A) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity.
References:Nicolin, A. et al.: Cancer, Chemother. Rep., 57, 3 (1973); Bonmassar, E. et al.: Cancer Res., 35, 1957 (1975);
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