CAS:327-74-2|2-Amino-5-cyanobenzotrifluoride

Catalogue Number:A603815
Chemical Name:2-Amino-5-cyanobenzotrifluoride
Synonyms:4-Amino-α,α,α-trifluoro-m-tolunitrile; 2-Amino-5-cyanobenzotrifluoride; 2-Trifluoromethyl-4-cyanoaniline; 3-Trifluoromethyl-4-aminobenzonitrile; 4-Amino-3-trifluoromethylbenzonitrile; 4-Cyano-2-trifluoromethylaniline
CAS Number:327-74-2
Molecular Formula:C₈H₅F₃N₂
Appearance:White to Light Beige Solid
Melting Point:66.9° – 67.9°C
Molecular Weight:186.13
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:2-Amino-5-cyanobenzotrifluoride is used in the design and synthesis of 4-phenylpyrrole derivatives as androgen receptor antagonists which show efficacy against prostate cancer cells.
References:Yamamoto, S. et al.: Bioorg. Med. Chem. Lett., 20, 422 (2012), Chen, J. et al.: Synth. Met., 160, 1953 (2010);
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