CAS:65514-71-8|[2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone

Catalogue Number:A603880
Chemical Name:[2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone
Synonyms:1-[2-[(2-Amino-4-chlorophenyl)amino]benzoyl]-4-methylpiperazine; Clozapine EP Impurity D; Clozapine EP Impurity D
Impurity:Clozapine EP Impurity D
CAS Number:65514-71-8
Molecular Formula:C₁₈H₂₁ClN₄O
Appearance:Pale Red to Red Solid
Melting Point:>103°C (dec.)
Molecular Weight:344.84
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:[2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone (Clozapine EP Impurity D) is used in the synthesis of substituted dibenzodiazepines. Also an impurity in the synthesis of Clozepine (C587500), an antipsychotic.
References:Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)
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