N6,N6-Bis[(5S)-6-(1,1-dimethylethoxy)-2,6-dioxo-5-[[(phenylmethoxy)carbonyl]amino]hexyl]-N2-[(phenylmethoxy)carbonyl]-L-lysine 1,1-Dimethylethyl Ester

Chemical Name:N6,N6-Bis[(5S)-6-(1,1-dimethylethoxy)-2,6-dioxo-5-[[(phenylmethoxy)carbonyl]amino]hexyl]-N2-[(phenylmethoxy)carbonyl]-L-lysine 1,1-Dimethylethyl Ester
CAS Number:204074-54-4
Molecular Formula:C₅₄H₇₄N₄O₁₄
Molecular Weight:1003.18
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N6,N6-Bis[(5S)-6-(1,1-dimethylethoxy)-2,6-dioxo-5-[[(phenylmethoxy)carbonyl]amino]hexyl]-N2-[(phenylmethoxy)carbonyl]-L-lysine 1,1-Dimethylethyl Ester is a reagent used in the synthesis of deoxypyridinoline, a biochemical marker of collagen turnover. Also, it is an intermediate used in the synthesis of Deoxypyridinoline Chloride Trihydrochloride Salt (D249900), which is a collagen cross-links agent. A primary reference material for the monitoring of bone metabolism.
References:Allevi, P., et al.: Chem. Comm., 559-560 (1999); Heaney, R., et al.: J. Bone Miner. Res., 5, 1135 (1990), Hannon, R., et al.: J. Bone Miner. Res., 13, 1124 (1998), Coudray, C., et al.: Eur. J. Nutr., 42, 91 (2003), Abrams, S., et al.: Am. J. Clin. Nutr., 82, 471 (2005)
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