CAS:625-05-8|3-Amino-3-methylbutanoic Acid, 90%

Catalogue Number:A608785
Chemical Name:3-Amino-3-methylbutanoic Acid, 90%
Synonyms:3-Amino-3-methylbutyric Acid; β-Aminoisovaleric Acid
CAS Number:625-05-8
Molecular Formula:C₅H₁₁NO₂
Appearance:White Solid
Melting Point:221-223°C
Molecular Weight:117.15
Storage:-20°C, Inert atmosphere
Solubility:Water (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Amino-3-methylbutanoic Acid acts as a reagent in the preparation of arylsulfonyl methylbutanamides of cycloalkylamines, particularly adamantylamines, as selective inhibitors of human and murine 11b-hydroxysteroid dehydrogenase type 1. Synthesis of acetylcholine and carbamoylcholine analogs as a functionally selective a4b2 nicotinic acetylcholine receptor agonist. Phenamide preparation by coupling reaction.
References:Lee, Y., et al.:Bioorg. Med. Chem. Lett., 24, 1421 (2014); Hansen, C. P., et al.: J. Med. Chem., 51, 7380 (2008); Makkar, N. S., et al.: J. Antibiot., 48, 369 (1995)
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