Esorubicin Hydrochloride

Chemical Name:Esorubicin Hydrochloride
Synonyms:(8S,10S)-10-[[(2S,4R,6S)-4-Aminotetrahydro-6-methyl-2H-pyran-2-yl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Hydrochloride;[2S-[2?(8R*,10R*),4?,6?]]-10-[(4-Aminotetrahydro-6-methyl-2H-pyran-2-yl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Hydrochloride; (8S,10S)-10-[[(2S,4R,6S)-4-Aminotetrahydro-6-methyl-2H-pyran-2-yl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Hydrochloride; 4′-Deoxyadriamycin Hydrochloride; 4′-Deoxydoxorubicin Hydrochloride; Deoxydoxorubicin Hydrochloride
CAS Number:63950-06-1
Alternate CAS #:Free Base: 63521-85-7
Molecular Formula:C₂₇H₃₀ClNO₁₀
Molecular Weight:563.98
Category:Research Tools;
Applications:Esorubicin Hydrochloride is the hydrochloride salt of Esorubicin and a derivative of Doxorubicin (D558000). Esorubicin is an anthracycline that has potential antiproliferative activity against human tumour cell lines and experiementally shows efficacy Doxorubicin-resistant malignancies.
References:Berens, M., et al.: Cancer Chemot. Pharm, 19, 301 (1987); Praet, M., et al.: Biochem. Pharmacol., 51, 1341 (1996); Rozencweig, M., et al.: Invest. New Drug., 1, 309 (1983)
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