CAS:7597-60-6|1,3-Dimethyl-4-amino-5-(formylamino)uracil

CAS:7597-60-6|1,3-Dimethyl-4-amino-5-(formylamino)uracil

Catalogue Number:A609570
Chemical Name:1,3-Dimethyl-4-amino-5-(formylamino)uracil
Synonyms:6-Amino-5-formamido-1,3-dimethyl-uracil; 1,3-Dimethyl-4-amino-5-(formylamino)uracil; 6-Amino-1,3-dimethyl-5-(formylamino)pyrimidine-2,4-dione; N-(6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-formamide; N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)formamide; NSC 42307
CAS Number:7597-60-6
Molecular Formula:C₇H₁₀N₄O₃
Appearance:White to Off-White Solid
Melting Point:252-254°C
Molecular Weight:198.18
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Miscellaneous;
Applications:6-Amino-5-1,3-dimethyl-5-(formamido)uracil is a substitued uracilic metabolite of methylxanthine and is also a metabolite of Theophylline (T343850). 6-Amino-5-1,3-dimethyl-5-(formamido)uracil has been used for the synthesis of 8-arylaminotheophyllines.
References:Peri, G., et. al.: Toxicol. Lett., 18, 133 (1983); Celardo, A., et. al.: Eur. J. Drug Metab. Ph., 10, 279 (1985); Senga, K., et. al.: J. Heterocyclic Chem., 15, 641 (1978)
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