Ethyl (13aS,13bS)-13a-Ethyl-10-methoxy-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]-pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate(Vinpocetine Related Compound C)

Chemical Name:Ethyl (13aS,13bS)-13a-Ethyl-10-methoxy-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]-pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate(Vinpocetine Related Compound C)
Synonyms:(13aS)-Ethyl 13a-Ethyl-8-methoxy-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate
Molecular Formula:C₂₃H₂₈N₂O₃
Molecular Weight:380.48
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Ethyl (13aS,13bS)-13a-ethyl-10-methoxy-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]-pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate, is an impurity of Vinpocetine (V332500), which is a semisynthetic derivative of the alkaloid vincamine with vasodilating activity. Vinpocetine has been also identified as a novel anti-inflammatory agent.
References:Han, et al.: J. Biol. Chem., 274, 22337 (1999), O’Donnell, et al.: Pharmacol. Biochem. Behav., 63, 185 (1999); Jeon, K., et al., Procee. Natio. Academy Sci., 107 (21), 9795 (2010);
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