CAS:61714-27-0|N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride

Catalogue Number:A610000
Chemical Name:N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride
Synonyms:W7
CAS Number:61714-27-0
Alternate CAS #
Free Base: 65595-90-6
Molecular Formula:C₁₆H₂₁ClO₂N₂S • HCl
Appearance:White to Off-White Solid
Melting Point:190-192?C
Molecular Weight:340.87 + 36.46
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:W7 is a vascular relaxing agent which affects vascular smooth muscle actomyosin. W7, an inhibitor of actomyosin superprecipitation, produces relaxation of isolated rabbit arterial strips and antagonizes the contraction of the strips induced by various contractile agonists. W7 is also a calmodulin antagonist that binds to calmodulin and inhibits Ca2+/calmodulin-regulated enzyme activities.
References:Hidaka, H., et al.: Proc. Nat. Acad. Sci. USA, 78, 4354 (1981)
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