CAS:13389-16-7|8-Amino-Inosine

Catalogue Number:A611855
Chemical Name:8-Amino-Inosine
Synonyms:NSC 109320;
CAS Number:13389-16-7
Molecular Formula:C₁₀H₁₃N₅O₅
Appearance:Off-White to Pale Beige Solid
Melting Point:>215°C (dec.)
Molecular Weight:283.24
Storage:4°C, Inert atmosphere
Solubility:DMSO (Slightly), Water (Slightly)
Category:Research Tools; Standards; Molecular Biology; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:8-Amino-Inosine is an derivative of Inosine (I661000), a nucleoside that is found in tRNAs and is essential for the proper translation of genetic code in a wobble base pair. Inosine is also known to exert neuroprotective properties and has been used to treat stroke patients to restore neural function. 8-Amino-Inosine have been studied as a potential chemotherapeutic agent for the treatment of leukemia function by the cytodestruction of the neoplastic cells.
References:Vandemeulebroucke A, et al. 2010. Biochemistry. 2010 Oct 19;49(41):8999-9010
Nestor G, et al. 2010. J Agric Food Chem. 2010 Oct 27;58(20):10799-803
Lin TS, et al. 1985. J Med Chem. 1985 Oct;28(10):1481-5.
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