CAS:56610-72-1|7b-Amino-7a-methoxy-3-(1-methyl-5-tetrazolylthio)methyl-3-cephem-4-carboxylic Acid Diphenylmethyl Ester

Catalogue Number:A612020
Chemical Name:7b-Amino-7a-methoxy-3-(1-methyl-5-tetrazolylthio)methyl-3-cephem-4-carboxylic Acid Diphenylmethyl Ester
Synonyms:(6R,7S)-7-Amino-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Diphenylmethyl Ester; 7-MAC; (6R-cis)-7-Amino-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Diphenylmethyl Ester; Diphenylmethyl 7β-Amino-7α-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-3-cephem-4-carboxylate;
CAS Number:56610-72-1
Molecular Formula:C₂₄H₂₄N₆O₄S₂
Appearance:Pale Yellow to Yellow Solid
Melting Point:>131ºC (dec.)
Molecular Weight:524.62
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly, Heated)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites; Semi-Synthetic;
Applications:7b-Amino-7a-methoxy-3-(1-methyl-5-tetrazolylthio)methyl-3-cephem-4-carboxylic Acid Diphenylmethyl Ester is a 7a-methoxycephalosporin derivative used as an intermediate in the preparation of Cefmetazole (C242850) and other semi-synthetic antibiotics.
References:Nakao, H. et al.: J. Antibiot., 29, 554 (1976); Nakayama, E. et al.: Sank. Kenk. Nen., 29, 147 (197); Nakao, H. et al.: J. Antibiot., 32, 320 (1979);
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