CAS:214358-33-5|N-(3-(Aminomethyl)benzyl)acetamidine Dihydrochloride

CAS:214358-33-5|N-(3-(Aminomethyl)benzyl)acetamidine Dihydrochloride

Catalogue Number:A614250
Chemical Name:N-(3-(Aminomethyl)benzyl)acetamidine Dihydrochloride
Synonyms:N-[[3-(Aminomethyl)phenyl]methyl]ethanimidamide Dihydrochloride; 1400W Dihydrochloride
CAS Number:214358-33-5
Alternate CAS #
Free Base: 180001-34-7
Molecular Formula:C₁₀H₁₇Cl₂N₃
Appearance:White to Pale Beige Solid
Melting Point:213-220°C
Molecular Weight:250.17
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Category:Research Tools; Enzyme Activators and Inhibitors;
Applications:N-(3-(Aminomethyl)benzyl)acetamidine Dihydrochloride is a selective inducible nitric oxide synthase (iNOS) inhibitor (1, 2, 3). A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM (1).
References:(1) Garvey, E.P., et al.: J. Biol. Chem. (1997) 272: 4959-63
(2) Thomsen, L.L., et al.: Cancer Res. (1997) 57: 3300-4
(3) Archer, E. J., et al.: ACS Synth. Biol. (2012) 1: 451–457
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