CAS:4442-59-5|2-Aminomethyl-1,4-benzodioxane

Catalogue Number:A615340
Chemical Name:2-Aminomethyl-1,4-benzodioxane
Synonyms:(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methanamine; (±)-2-(Aminomethyl)-1,4-benzodioxane; 1,4-Benzodioxane-2-methylamine; 2-(Aminomethyl)-1,4-benzodioxan; 2-Aminomethyl-1,4-benzodioxane; 2-Aminomethyl-2,3-dihydro-1,4-benzodioxin; Fourneau 946; LP 1; LP 1 (pharmaceutical); N-[(2,3-Dihydrobenzo[1,4]dioxin-2-yl)methyl]amine; NSC 116045; [(2,3-Dihydro-1,4-benzdioxin-2-yl)methyl]amine; [(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]amine
CAS Number:4442-59-5
Molecular Formula:C₉H₁₁NO₂
Appearance:Clear Colorless Oil
Molecular Weight:165.19
Storage:4°C, Hygroscopic
Solubility:Chloroform, Ethyl Acetate
Category:Building Blocks; Miscellaneous;
Applications:2-Aminomethyl-1,4-benzodioxane is used in the synthesis of N-substituted (dihydrobenzodioxinyl)methylamine derivatives as D2 antagonists/5-HT1A partial agonists with potential as atypical antipsychotic agents in relation to affinity for a1 adrenoceptors.
References:Birch, A. M., et al.: J. Med. Chem., 42, 3342 (1999);
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