CAS:306280-98-8|3-Amino-​5-​phenyl-thieno[2,​3-​d]​pyrimidin-​4(3H)​-​one

Catalogue Number:A617090
Chemical Name:3-Amino-​5-​phenyl-thieno[2,​3-​d]​pyrimidin-​4(3H)​-​one
CAS Number:306280-98-8
Molecular Formula:C₁₂H₉N₃OS
Molecular Weight:243.28
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:3-Amino-​5-​phenyl-thieno[2,​3-​d]​pyrimidin-​4(3H)​-​one is a related compound of Barbadin (B118250), a selective β-arrestin/β2-adaptin inhibitor that selectively inhibits the interaction between b-arrestin and the b2-adaptin subunit of the clathrin adaptor protein AP2 without affecting the formation of receptor/b-arrestin complexes.
References:Beautrait, A., et al.: Nat Commun. 8, 15054 (2017)
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