CAS:243145-00-8|1-Amino-3-nitroadamantane

Catalogue Number:A618130
Chemical Name:1-Amino-3-nitroadamantane
Synonyms:3-Nitrotricyclo[3.3.1.13,7]decan-1-amine
Impurity:Vildagliptin Impurity:CAS Number:243145-00-8
Molecular Formula:C₁₀H₁₆N₂O₂
Appearance:Pale Brown to Brown Sticky Solid
Molecular Weight:196.25
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:1-Amino-3-nitroadamantane has potential application in co-catalyst for transition metal reactions and maybe a useful intermediate for the synthesis of Vildagliptin (V305000), an antidiabetic drug that inhibits dipeptidyl peptidase 4 (DPP-4). Vildagliptin exhibits antioxidant properties and may be an apoptotic compound against pancreatic cancer cells.
References:Amritha, C., et al.: JCDR 9, FC14 (2015); Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004)
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