CAS:537034-15-4|N-(2-Aminophenyl)-N’-phenylheptanediamide

Catalogue Number:A625980
Chemical Name:N-(2-Aminophenyl)-N’-phenylheptanediamide
Synonyms:N1-(2-Aminophenyl)-N7-phenylheptanediamide;
CAS Number:537034-15-4
Molecular Formula:C₁₉H₂₃N₃O₂
Appearance:Off-White to Pale Brown Solid
Melting Point:155-157°C
Molecular Weight:325.4
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Histone deacetylase inhibitor IV. A cell-permeable pimeloylanilide compound that acts as a FXN-(frataxin gene) specific HDAC inhibitor. Reverses the silencing of FXN transcription in FRDA (Friedrich’s ataxia) cells due to hypoacetylation of histones H3 and H4.
References:Dunah, A., et al.: Science, 296, 2238
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