CAS:216060-08-1|4-Amino-2-methylphenylboronic Acid

Catalogue Number:A627995
Chemical Name:4-Amino-2-methylphenylboronic Acid
CAS Number:216060-08-1
Molecular Formula:C₇H₁₀BNO₂
Molecular Weight:150.97
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Amino-2-methylphenylboronic Acid is an intermediate used to prepare indole derivatives having combined 5HT1A, 5HT1B, and 5HT1D receptor antagonist activity. It is also an impurity of Tavaborole (T009760), a topical treatment of toenail onychomycosis.
References:Gaster, L., et al.: PCT Int. Appl. (1998), WO 9850358 A1 19981112; Toledo-Bahena, M.E. et. al.: J. Drugs Dermatol., 13, 1124 (2014)
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