CAS:20386-22-5|1-Aminopyrrolidin-2-one Hydrochloride

Catalogue Number:A628805
Chemical Name:1-Aminopyrrolidin-2-one Hydrochloride
Synonyms:1-Amino-2-pyrrolidinone Hydrochloride; 1-Amino-2-pyrrolidinone Monohydrochloride; 1-Aminopyrrolidin-2-one Hydrochloride; N-Amino-2-pyrrolidinone Hydrochloride
CAS Number:20386-22-5
Alternate CAS #
Free Base: 6837-14-5
Molecular Formula:C₄H₉ClN₂O
Appearance:White to Pale Beige Solid
Melting Point:143-148°C
Molecular Weight:136.58
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Category:Building Blocks; Enzyme Activators and Inhibitors;
Applications:1-Aminopyrrolidin-2-one Hydrochloride is used for the optimization of dihydropyrrolopyrazole series for transforming the growth factor-b type I receptor kinase domain inhibitor and also for the discovery of an orally bioavailable antitumor agent.
References:Li, H., et al.: J. Med. Chem., 51, 2302 (2008)
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