CAS:123536-14-1|(3R)-Aminoquinuclidine Dihydrochloride

Catalogue Number:A629195
Chemical Name:(3R)-Aminoquinuclidine Dihydrochloride
Synonyms:(R)-1-Azabicyclo[2.2.2]octan-3-amine Dihydrochloride, ; (3R)-3-Aminoquinuclidine Dihydrochloride; (R)-(+)-3-Aminoquinuclidine Dihydrochloride; (R)-3-Aminoquinuclidine Dihydrochloride; (R)-Quinuclidin-3-amine Dihydrochloride; 3-(R)-Aminoquinuclidine Dihydrochloride;
CAS Number:123536-14-1
Alternate CAS #
freebase: 123536-15-2
Molecular Formula:C₇H₁₆Cl₂N₂
Appearance:White to Light Beige Solid
Melting Point:>275°C (dec.)
Molecular Weight:199.12
Storage:4°C
Solubility:DMSO (Sparingly), Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Chiral Molecules;
Applications:(3R)-Aminoquinuclidine is used in the preparation of serotonin type 3 (5-HT3) receptor antagonist as potential new drugs for the treatment of irritable bowel syndrome (IBS).
References:Manning, D.D. et al.: Bioorg. Med. Chem. Lett., 21, 58 (2011); Langlois, M. et al.: Eur. J. Med. Chem., 29, 925 (1994);
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