3-Hydroxy-cis-5-tetradecenoylcarnitine Inner Salt

Chemical Name:3-Hydroxy-cis-5-tetradecenoylcarnitine Inner Salt
Synonyms:(4S)-4-(((Z)-3-Hydroxytetradec-5-enoyl)oxy)-4-(trimethylammonio)butanoate
Molecular Formula:C₂₁H₃₉NO₅
Molecular Weight:385.54
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Hydroxy-cis-5-tetradecenoylcarnitine Inner Salt is a derivative of Carnitine, essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado. 3-Hydroxy-cis-5-tetradecenoylcarnitine works similar to the endogenous non-toxic molecule L-Carnitine (C184110) whose bioavailablity is improved due to the transport systems in place for Carnitine.
References:Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978), Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001), Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002), Karlic, H., et al.: Nutrition, 20, 709 (2004), O. Piermatti. et al.: Bioorg. Med. Chem., 16, 1444 (2008);
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