CAS:1086380-23-5|2-Amino-5-(trifluoromethyl)-4-thiazolecarboxylic Acid

Catalogue Number:A633310
Chemical Name:2-Amino-5-(trifluoromethyl)-4-thiazolecarboxylic Acid
Synonyms:2-Amino-5-(trifluoromethyl)thiazole-4-carboxylic Acid
CAS Number:1086380-23-5
Molecular Formula:C₅H₃F₃N₂O₂S
Molecular Weight:212.15
Category:Building Blocks; Miscellaneous;
Applications:2-Amino-5-(trifluoromethyl)-4-thiazolecarboxylic Acid is a derivative of 2-Aamino-4-thiazolecarboxylic Acid Ethyl Ester (E678465), a chemical reagent used in the preparation fo SAR thiazolamino arylaminopyrimidines as anaplastic lymphoma kinase inhibitors. As well as in the synthesis of 4-bicyclick piperadine derivatives as potent stearoyl-CoA desaturase (SCD1) inhibitors in the treatment of cancer.
References:Liu, Z. et al.: Eur. J. Med. Chem., 86, 438 (2014); Noto, A. et al.: Cell Death Disease, 4, e947 (2013);
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