CAS:140171-49-9|Amlodipine 2-Phthalimide

CAS:140171-49-9|Amlodipine 2-Phthalimide

Catalogue Number:A633565
Chemical Name:Amlodipine 2-Phthalimide
Synonyms:4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3,5-Diethyl Ester; Diethyl 4-(2-Chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;
CAS Number:140171-49-9
Molecular Formula:C₂₉H₂₉ClN₂O₇
Appearance:Pale Yellow Solid
Melting Point:98-101°C
Molecular Weight:553
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Slightly, Heated)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Amlodipine Diethyl Ether Phthalimide is the impurity of the drug Amlodipine (A633500), which is dihydropyridine calcium channel blocker, used as an antianginal and antihypertensive.
References:Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996);
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