CAS:739366-20-2|Anagliptin

Catalogue Number:A637210
Chemical Name:Anagliptin
Synonyms:N-[2-[[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide; N-[2-([2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide; Suiny
CAS Number:739366-20-2
Molecular Formula:C₁₉H₂₅N₇O₂
Appearance:White to Off-White Solid
Melting Point:115 – 119°C
Molecular Weight:383.45
Storage:4°C
Solubility:Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
Category:Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Anagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction. It also attenuates atherosclerosis in male apolipoprotein E-deficient mice.
References:Ervinna, N., et al.: Endocrinology, 154, 1260 (2013); Furuta, S., et al.: Eur. J. Drug Metab. Ph., 38, 87 (2013)
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