Carboxy Dabrafenib Disodium Salt

Chemical Name:Carboxy Dabrafenib Disodium Salt
Synonyms:5-(2-Amino-4-pyrimidinyl)-4-[3-[[(2,6-difluorophenyl)sulfonyl]amino]-2-fluorophenyl]-α,α-dimethyl-2-thiazoleacetic Acid Disodium Salt
CAS Number:1195767-90-8
Alternate CAS #:1195873-54-1
Molecular Formula:C₂₃H₁₇F₃N₅Na₂O₄S₂
Molecular Weight:594.52
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:Carboxy Dabrafenib Disodium Salt is a sodium salt of Carboxy Dabrafenib, a metabolite of Dabrafenib (D101000). Dabrafenib is an inhibitor of BRAF V600E used in the treatment metastatic melanoma.
References:Vikingsson, Svante, et al.: Analy. and Bioanaly. Chem., 409(15), 3749-3756 (2017);Bershas, David A., et al.: Drug Metabol. & Dispos., 41(12), 2215-2224 (2013)
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