CAS:1054543-47-3|Apoptozole

Catalogue Number:A729045
Chemical Name:Apoptozole
Synonyms:4-[[2-[3,5-Bis(trifluoromethyl)phenyl]-4,5-bis(4-methoxyphenyl)-1H-imidazol-1-yl]methyl]-benzamide;
CAS Number:1054543-47-3
Molecular Formula:C₃₃H₂₅F₆N₃O₃
Appearance:White Solid
Melting Point:225-228°C
Molecular Weight:625.56
Storage:4°C
Solubility:DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:Apoptozoleis an inhibitor of heat shock protein 70 (Hsp70) and acts by blocking its ATPase activity. Induces apoptosis in cancer cells.
References:Ko, S. et al.: Chem. Biol., 22, 391 (2015); Ljung, B. et al.: J. Cardiovasc. Pharmacol., 15, S11 (1990);
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