CAS:197904-84-0|Apricoxib

Catalogue Number:A729850
Chemical Name:Apricoxib
Synonyms:4-[2-(4-Ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]benzenesulfonamide; 4-Methyl-2-(4-ethoxyphenyl)-1-(4-sulfamoylphenyl)pyrrole; CS 706; R 109339; TG 01;
CAS Number:197904-84-0
Molecular Formula:C₁₉H₂₀N₂O₃S
Appearance:Yellow Solid
Melting Point:148-151°C
Molecular Weight:356.44
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Apricoxib, is an orally active, selective COX-2 inhibitor, used as as an analgesic and anti-inflammatory agent, and also has anticancer potential, since COX-2 inhibition can reduce tumor growth and augment therapy.
References:Kirane, A, et al.: Clinical Cancer Res., 18, 5031 (2012); Rohatagi, Sh., et al.: British J. Clin. Pharmaco., 66, 60 (2008);
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