CAS:630420-16-5|Asunaprevir

Catalogue Number:A788753
Chemical Name:Asunaprevir
Synonyms:(1R,2S)-N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(7-chloro-4-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenylcyclopropanecarboxamide; 1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1R,2S)-2-vinylcyclopropane-1-carboxamide; Asunaprevir; BMS 650032; Sunvepra
CAS Number:630420-16-5
Molecular Formula:C₃₅H₄₆ClN₅O₉S
Appearance:White to Off-White Solid
Melting Point:149-150oC
Molecular Weight:748.29
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Asunaprevir is an inhibitor of the viral enzyme serine protease HCV NS3. Also functions as a second generation NS3/4A protease inhibitor used in the treatment of hepatitis C.
References:Takehara, T., et al.: Igaku no Ayumi, 255, 1155 92015); Kalaghatgi, P., et al.: PLoS One, 11, 5 (2016)
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