CAS:896466-04-9|AT-9283

Catalogue Number:A790300
Chemical Name:AT-9283
Synonyms:AT 9283; 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea; N-Cyclopropyl-N’-[3-[5-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-urea
CAS Number:896466-04-9
Molecular Formula:C₁₉H₂₃N₇O₂
Appearance:Off-White Solid
Melting Point:>164°C (dec.)
Molecular Weight:381.43
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Research Tools; Enzyme Activators and Inhibitors;
Applications:AT-9283 is a potent AuroraA/AuroraB and multi-kinase inhibitor. AT-9283 has shown to inhibit growth and survival of multiple solid tumor cell lines and is efficacious in mouse xenograft models. It is a COVID19-related research product.
References:Curry, J., et. al.: Cell Cycle, 8, 1921 (2009)
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