CAS:876725-64-3|(3R)-3-Amino-2,3-dihydro-1H-inden-1-one Hydrochloride

Catalogue Number:A790308
Chemical Name:(3R)-3-Amino-2,3-dihydro-1H-inden-1-one Hydrochloride
Synonyms:(3R)-3-Amino-2,3-dihydro-1H-inden-1-one Hydrochloride (1:1)
CAS Number:876725-64-3
Molecular Formula:C₉H₉NO • (HCl)
Molecular Weight:147.17 + (36.46)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(3R)-3-Amino-2,3-dihydro-1H-inden-1-one Hydrochloride is an intermediate in the synthesis of (3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one (D449765), which is a building block in the preparation of Rasagiline (R126000), which is a selective irreversible MAO-B inhibitor. Rasagiline is also an Antiparkinsonian agent.
References:Rabey, J.M., et al.: Clin. Neuropharmacol., 23, 324 (2000); Glezer, S., et al.: Eur. J. Pharmacol., 472, 173 (2003); Youdim, M.B.H., et al.: Biochem. Pharmacol., 66, 1635 (2003); Chen, J.J., et al.: J. Clin. Pharmacol., 45, 878 (2005)
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