Catalogue Number:A791870
Chemical Name:Atorvastatin 3-Isopropyl Ether tert-Butyl Ester
Synonyms:(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-3-isopropyl Ether tert-Butyl Ester;
CAS Number:1797009-04-1
Molecular Formula:C₄₀H₄₉FN₂O₅
Molecular Weight:656.83
Category:Building Blocks;
Applications:An impurity in the synthesis of Atorvastatin (A791750(P)), which is a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References:Shaw, M.K., et al., Biochem. Biophys. Res. Commun. 170(2), 726-734 (1990)
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Posted inMaterials
CAS:1797009-04-1|Atorvastatin 3-Isopropyl Ether tert-Butyl Ester
