CAS:137732-39-9|cis-Atovaquone (Racemic)

Catalogue Number:A793450
Chemical Name:cis-Atovaquone (Racemic)
Synonyms:cis-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione; USP Atovaquone Related Compound A; Atorvastatin EP Impurity B
Impurity:Atorvastatin EP Impurity B
CAS Number:137732-39-9
Molecular Formula:C₂₂H₁₉ClO₃
Appearance:Pale Yellow to Light Yellow Solid
Melting Point:>40°C (dec.)
Molecular Weight:366.84
Storage:20°C, Inert atmosphere
Solubility:Chloroform (Slightly), Dichloromethane (Slightly, Acetonitrile
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:cis-Atovaquone (Atorvastatin EP Impurity B) is the cis-isomer of Atovaquone (A793500), a hydroxynaphthoquinone derivative that inhibits mitochondrial electron transport.
References:Hudson, A.T., et al.: Drugs Exp. Clin. Res., 17, 427 (1991), Fry, M., et al.: Biochem. Pharmacol., 43, 1545 (1992), El-Sadr, W.M., et al.: N. Engl. J. Med., 339, 1889 (1998),
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