CAS:494772-86-0|3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide

Catalogue Number:A794800
Chemical Name:3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide
Synonyms:3-[(Aminocarbonyl)amino]-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide;
CAS Number:494772-86-0
Molecular Formula:C₁₇H₂₀N₄O₃S
Appearance:Pale Yellow to Light Yellow Solid
Melting Point:>200°C (dec.)
Molecular Weight:360.43
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide is a transforming growth factor (TGF)-b-activated kinase 1 (TAK-1) inhibitor. 3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide has potential use in the treatment of certain lymphomas that are particularly susceptible to TAK1 inhibitors such as B cell tumors, solid tumors, or T cell leukemias.
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