CAS:885126-35-2|Axitinib Tetrahydro-2H-pyran

Catalogue Number:A795135
Chemical Name:Axitinib Tetrahydro-2H-pyran
Synonyms:N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-yl]thio]benzamide; Axitinib Impurity 14
CAS Number:885126-35-2
Molecular Formula:C₂₇H₂₆N₄O₂S
Appearance:Pale Brown to Light Brown Solid
Melting Point:143 – 145°C
Molecular Weight:470.59
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Axitinib Tetrahydro-2H-pyran is an intermediate in the synthesis of Axitinib (A794650). The Tetrahydro-2H-pyran moiety acts as a protecting group.
References:Zhai, L., et al.: Org. Process Res. Dev., 19, 849-857 (2015)
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