CAS:1421373-98-9|AZ 5104

Catalogue Number:A795170
Chemical Name:AZ 5104
Synonyms:N-(5-((4-(1H-Indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide
CAS Number:1421373-98-9
Molecular Formula:C₂₇H₃₁N₇O₂
Appearance:White to Off-White Solid
Melting Point:158 – 160°C
Molecular Weight:485.58
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:AZ 5104 is a derivative of AZD 9291 (A808075) is a selective EGFR inhibitor (epidermal growth factor receptor), used in the treatments of nonsmall-cell lung cancer (NSCLC).
References:Finlay, M.R.V., et al.: J. Med. Chem., 57, 8249 (2014);
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