CAS:79200-56-9|(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one

Catalogue Number:A795205
Chemical Name:(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one
Synonyms:(1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one; (-)-2-Azabicyclo[2.2.1]hept-5-en-3-one; (-)-Vince Lactam; Abacavir – In House Impurity; Abacavir Impurities
Impurity:Abacavir – In House Impurity:CAS Number:79200-56-9
Molecular Formula:C₆H₇NO
Appearance:Off-White Solid
Melting Point:95-98ºC
Molecular Weight:109.13
Storage:4°C
Solubility:Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Chiral Molecules;
Applications:(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one (Abacavir – In House Impurity) is an Abacavir (A105000) intermediate (1). It is also an intermediate in the synthesis of carbocyclic sugar amines, carbanucleosides, and carbocyclic dinucleotide analogues (2).
References:(1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012)
(2) Slama, J.T., et al.: Biochemistry, 27, 183 (1988)
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