CAS:320-67-2|5-Azacytidine

Catalogue Number:A796000
Chemical Name:5-Azacytidine
Synonyms:Azacitidine; 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one; 5-AC; 5-AZC; 5-AZCR; 5-AzaC; Antibiotic U 18496; Azacytidine; Ladakamycin; Ledakamycin; Mylosar; NSC 102816; NSC 103-627; U 18496; Vidaza; WR 183027;
CAS Number:320-67-2
Molecular Formula:C₈H₁₂N₄O₅
Appearance:White to Off-White Solid
Melting Point:>196ºC (dec.)
Molecular Weight:244.2
Storage:-20°C
Solubility:Methanol (Slightly, Heated), Water (Slightly, Heated, Sonicated)
Category:Standards; Nucleic Acid; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
Applications:A potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase.
References:Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999), Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999), Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999), Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)
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