CAS:1356962-20-3|AZD3463

Catalogue Number:A808105
Chemical Name:AZD3463
Synonyms:N-(4-(4-Aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine
CAS Number:1356962-20-3
Molecular Formula:C₂₄H₂₅ClN₆O
Molecular Weight:448.95
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:AZD3463, is a novel ALK/IGF1R dual Inhibitor, having the ability of overcoming multiple mechanisms of acquired resistance to Crizotinib (C785000).
References:Zou, H.Y. et al.: Cancer Res., 67, 4408 (2007); Cui, J.J. et al.: J. Med. Chem., No pp given (2011); Sasaki, T. et al.: Cancer. Res. et al.: 70, 10038 (2010);
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