CAS:1627494-13-6|AZD 8186

Catalogue Number:A808185
Chemical Name:AZD 8186
Synonyms:8-[(1R)-1-[(3,5-Difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide
CAS Number:1627494-13-6
Molecular Formula:C₂₄H₂₅F₂N₃O₄
Appearance:White to Off-White Solid
Melting Point:226-227°C
Molecular Weight:457.48
Storage:-20°C
Solubility:DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:AZD 8186 is a potent and selective inhibitor of PI3Kb and PI3Kδ for the treatment of PTEN-deficient cancers.
References:Barlaam, B., et al.: J. Med. Chem., 58, 943 (2015)
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