Daclatasvir Diethyl Ester-d10

Chemical Name:Daclatasvir Diethyl Ester-d10
Synonyms:N,N’-[[1,1′-Biphenyl]-4,4′-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxoethyl]]]biscarbamic Acid C,C’-Diethyl Ester-d10
Alternate CAS #:Unlabelled: 1009113-58-9
Molecular Formula:C₄₂H₄₄D₁₀N₈O₆
Molecular Weight:776.99
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
Applications:Daclatasvir Diethyl Ester-d10 is the isotope labelled analog of Daclatasvir Diethyl Ester (D101525); an impurity of Daclatasvir (D101500) which is a compound that inhibits the HCV protein NS5A, and thus can be used as a drug candidate for the treatment of hepatitis C (HCV).
References:Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010)
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