4,5-Desbromo 4,5-Chloro-N-propylmethanesulfoamide Macitentan

Chemical Name:4,5-Desbromo 4,5-Chloro-N-propylmethanesulfoamide Macitentan
Synonyms:1-(5-(4-Chlorophenyl)-6-(2-((5-chloropyrimidin-2-yl)oxy)ethoxy)pyrimidin-4-yl)-N-propylmethanesulfonamide
Molecular Formula:C₂₀H₂₁Cl₂N₅O₄S
Molecular Weight:498.38
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4,5-Desbromo 4,5-Chloro-N-propylmethanesulfoamide Macitentan is an impurity of Macitentan (M105005); a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension.
References:Emoto, N. Ensho to Men’eki, 20, 487 (2012); Bruderer, S., et al.: Xenobiotica, 42, 901 (2012)
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