CAS:104862-31-9|[2R-(2a,3b,6a)]-3-Azido-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid 5,5-Dioxide Diphenylmethyl Ester

Catalogue Number:A926600
Chemical Name:[2R-(2a,3b,6a)]-3-Azido-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid 5,5-Dioxide Diphenylmethyl Ester
Synonyms:(2R,6R)-Benzhydryl 3-Azido-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylate 5,5-Dioxide;
CAS Number:104862-31-9
Molecular Formula:C₂₁H₂₀N₄O₅S
Appearance:White to Off-White Solid
Melting Point:137-139°C
Molecular Weight:440.47
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:[2R-(2a,3b,6a)]-3-Azido-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid 5,5-Dioxide Diphenylmethyl Ester is an intermediate in the synthesis of Tazobactam Sodium Salt-13C2,15N1 (T010102), which is a labelled analogue of Tazobactam Sodium Salt (T010100), which is a b-Lactamase inhibitor, used with b-lactam antibiotics to enhance their effect.
References:Gould, I.M., et al.: Drugs Exp. Clin. Res., 17, 187 (1991); Roland, R.K., et al.: J. Infect. Dis., 4, 226 (2000), Bonomo, R.A., et al.: Biochim. Biophys. Acta, 1547, 196 (2001);
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