CAS:1696392-12-7|Azilsartan Amide Medoxomil

Catalogue Number:A926915
Chemical Name:Azilsartan Amide Medoxomil
Synonyms:1-[[2′-(Aminocarbonyl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester
CAS Number:1696392-12-7
Molecular Formula:C₂₉H₂₅N₃O₇
Appearance:Off-White to Pale Yellow Solid
Melting Point:172 – 176°C
Molecular Weight:527.52
Storage:-20°C
Solubility:Acetone (Slightly), DMSO (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Azilsartan Amide Medoxomil is an impurity from the synthesis of Azilsartan Medoxomil (A926910). Azilsartan medoxomil is a long-acting angiotensin II receptor blocker (ARB) that is used to lower hypertension. When Azilsartan medoxomil enters the gastrointestinal tract, it is rapidly converted to its active form, Azilsartan (A926900).
References:Anon., IP.com Journal (2014), 14(10A), 1-22; Baker, W. & White, W.: Pharmacotherapy, 45, 1506 (2011); Cushman, W., et al.: Hypertension, 60, 310 (2012); Lastra, G., et al.: Cardio. Med. 3, 154 (2013); Miura, S., et al.: Hypertens. Res., 36, 134 (2012); Rakugi, H., et al.: Hypertens. Res., 35, 552 (2012)
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