CAS:3306-69-2|2-Azabicyclo[2.2.2]octan-3-one

Catalogue Number:A965798
Chemical Name:2-Azabicyclo[2.2.2]octan-3-one
Synonyms:3-Isoquinuclidinone; 3-Isoquinuclidone; 4-Aminocyclohexanecarboxylic acid lactam; Isonortropinone; NSC 85851
CAS Number:3306-69-2
Alternate CAS #
1193-65-3
Molecular Formula:C₇H₁₁NO
Appearance:White to Off-White Solid
Melting Point:192-194 °C
Molecular Weight:125.17
Storage:-20°C, Inert atmosphere
Solubility:Methanol (Slightly), Water (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:2-Azabicyclo[2.2.2]octan-3-one (cas# 3306-69-2) is used in the preparation of quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or tyrosine kinases. It is also used in the preparation of phenyl derivatives containing inhibitors of coagulation factor for prophylaxis and/or therapy of thromboembolic disorders.
References:Myers, M., et al.: PCT Int. Appl. (1998), WO 9854158 A1; Dorsch, D., et al.: PCT Int. Appl. (2002), WO 2002057236 A1
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