CAS:256376-24-6|BAY 41-2272

Catalogue Number:B118920
Chemical Name:BAY 41-2272
Synonyms:5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine
CAS Number:256376-24-6
Molecular Formula:C₂₀H₁₇FN₆
Appearance:White to Off-White Solid
Melting Point:209-213°C
Molecular Weight:360.39
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly. Heated)
Category:Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:BAY 41-2272 is a soluble guanylate cyclase agonist that activates human mononuclear phagocytes. Inhibits vascular smooth muscle growth through the cAMP-dependent protein kinase and cGMP-dependent protein kinase pathways.
References:Soeiro-Pereira, P. et al.: British. J. Pharmacol., 166, 1617 (2012); Joshi, C. et al.: J. Pharmacol. Exp. Ther., 339, 394 (2011)
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